ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,539,327, issued on Feb. 3, was assigned to Children's Hospital Medical Center (Cincinnati).

"Norovirus S particle based vaccines and methods of making and using same" was invented by Ming Tan (Cincinnati) and Xi Jiang (Cincinnati).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are vaccine compositions, in particular, polyvalent icosahedral compositions for antigen presentation. The disclosed compositions may contain an S particle made up of recombinant fusion proteins. The recombinant fusion proteins may include a norovirus (NoV) S domain protein, a linker protein domain operatively connected to the norovirus S domain protein, and an anti...