US Patent Issued to Children's Hospital Medical Center on April 22 for "VLP-based bivalent Ebola vaccines and methods of making and using same" (Ohio Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,100, issued on April 22, was assigned to Children's Hospital Medical Center (Cincinnati).

"VLP-based bivalent Ebola vaccines and methods of making and using same" was invented by Karnail Singh (Deerfield Township, Ohio) and Paul Spearman (Cincinnati).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are virus-like particle (VLP)-based bivalent vaccine compositions. The compositions may comprise a spherical retroviral Group-specific Antigen ("Gag") protein core and at least two Ebola glycoproteins. The at least two Ebola glycoproteins may be located at the exterior surface of the spherical Gag protein core, such that the VLP-based vaccine...