ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,246, issued on July 15, was assigned to Cheng-Yao Chen (Hsinchu, Taiwan).

"Method, kit and system for end labeling of nucleic acids" was invented by Cheng-Yao Chen (Hsinchu, Taiwan) and Yi-Wen Cheng (Hsinchu, Taiwan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a method for labeling a nucleic acid, including providing a target nucleic acid to be labeled; providing a 5'-end glycosylase to react with the target nucleic acid to create an intermediate nucleic acid having an abasic site at a 5'-end; and providing an aldehyde-reactive compound carrying a detectable label for coupling with the intermediate nucleic acid to form a labeled nuclei...