ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,472,245, issued on Nov. 18, was assigned to CHAIN BIOTECHNOLOGY Ltd. (Oxford, Great Britain).

"Compositions and methods" was invented by Edward Green (Oxford, Great Britain), Benjamin Michael Bradley (Oxford, Great Britain), Shisong Jiang (Oxford, Great Britain) and Richard Mark Edwards (Oxford, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "A bacterium of the class Clostridia comprising a heterologous nucleic acid molecule encoding at least one antigen, wherein the bacterium is capable of expressing the antigen in an intracellular compartment of the bacterium during anaerobic cell growth, and wherein at least one antigen is an infectious ...