ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,392, issued on Oct. 21, was assigned to Cephalon LLC (West Chester, Pa.).

"Spiropiperidine derivatives" was invented by Robert L. Hudkins (Chester Springs, Pa.), David B. Whitman (Phoenixville, Pa.), Craig A. Zificsak (Downingtown, Pa.), Allison L. Zulli (Chesterbrook, Pa.) and Melody McWherter (Boyertown, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are spiropiperidine compounds according to Formula I that have demonstrated activity as fatty acid synthase inhibitors. Also described herein are pharmaceutical compositions containing the described spiropiperidine compounds, and methods of treating diseases mediated by fatty acid...