US Patent Issued to CENTRILLION TECHNOLOGY HOLDINGS on March 25 for "Disulfide-linked reversible terminators" (California Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,368, issued on March 25, was assigned to CENTRILLION TECHNOLOGY HOLDINGS Corp. (Grand Cayman, Cayman Islands).

"Disulfide-linked reversible terminators" was invented by Moti Jain (Palo Alto, Calif.) and Wei Zhou (Palo Alto, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of sequencing polynucleotides and compounds, compositions useful for sequencing of polynucleotides. The chemical compounds include nucleotides and their analogs which possess a sugar moiety comprising a cleavable chemical group capping the 3'-OH group and a base that is attached to a detectable label through a cleavable linker comprisin...