ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,634, issued on March 25, was assigned to Centre for Novostics (New Territories, Hong Kong).
"Fragmentation for measuring methylation and disease" was invented by Yuk-Ming Dennis Lo (Hong Kong), Rossa Wai Kwun Chiu (Hong Kong), Kwan Chee Chan (Hong Kong), Peiyong Jiang (Hong Kong), Qing Zhou (Hong Kong), Guannan Kang (Hong Kong), Rong Qiao (Hong Kong) and Lu Ji (Hong Kong).
According to the abstract* released by the U.S. Patent & Trademark Office: "Fragmentation of cell-free DNA molecules is measured and used for various purposes, including determining methylation, e.g., at a particular site of a DNA molecule, at a particular genomic site in a reference genome for a biological sa...