ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,699, issued on March 18, was assigned to CELLECTIS (Paris).
"Method for generating t-cells compatible for allogenic transplantation" was invented by Laurent Poirot (Paris), David Sourdive (Levallois-Perret, France), Philippe Duchateau (Dravell, France) and Jean-Pierre Cabaniols (Saint Lau la Foret, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention pertains to engineered T-cells, method for their preparation and their use as medicament, particularly for immunotherapy. The engineered T-cells of the invention are characterized in that the expression of beta 2-microglobulin (B2M) and/or class II major histocompatibility comple...