ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,744, issued on Jan. 27, was assigned to CELLECTIS S.A. (Paris).

"Methods to genetically modify cells for delivery of therapeutic proteins" was invented by Alexandre Juillerat (New York), Philippe Duchateau (Draveil, France), Patrick Hong (New York), Laurent Poirot (Paris), Brian Busser (New York) and Alex Boyne (Jersey City, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods to genetically modify cells by insertion of an artificial exon (ArtEx) for delivery of therapeutic proteins in specific cell types and more particularly engineered cells for expression of a transgene into the brain of a patient."

The pat...