ALEXANDRIA, Va., June 16 -- United States Patent no. 12,306,192, issued on May 20, was assigned to Cedars-Sinai Medical Center (Los Angeles).
"Method of detecting cognitive impairment" was invented by Maya Koronyo (Los Angeles), Haoshen Shi (Los Angeles), Yosef Koronyo (Los Angeles) and Keith L. Black (Los Angeles).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention describes a method for the detection, diagnosis and monitoring of cognitive impairment and Alzheimer's disease. The method involves the detection of pericyte loss and deficiency in PDGFRBeta, alone or in combination with retinal vascular ABeta deposits. The method also involves detecting an alteration in blood-retinal barrier (BRB...