US Patent Issued to CASSIOPEA on June 24 for "Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives" (Italian Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,337,002, issued on June 24, was assigned to CASSIOPEA S.P.A. (Lainate, Italy).

"Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives" was invented by Mauro Ajani (Lainate, Italy) and Luigi Moro (Cairate, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention refers to a new enzymatic process for obtaining 17Alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17Alpha,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17Alpha-propionate and 9,11-deh...