ALEXANDRIA, Va., March 12 -- United States Patent no. 12,247,228, issued on March 11, was assigned to CASE WESTERN RESERVE UNIVERSITY (Cleveland).

"Non-covalent loading of plant picovirus particles" was invented by Nicole Steinmetz (San Diego) and Daniel Popkin (Cleveland).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of non-covalently loading a plant picornavirus is described. The method includes contacting a plant picornavirus in solution with a molar excess of a cargo molecule to load the plant picornavirus with the cargo molecule, and then purifying the loaded plant picornavirus. Examples of cargo molecules include imaging agents, antitumor agents, and antiviral agents. Loaded plant picornavirus...