US Patent Issued to Case Western Reserve University on Feb. 18 for "Methods and compositions for detecting esophageal neoplasias and/or metaplasias in the esophagus" (Ohio Inventors)

ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,810, issued on Feb. 18, was assigned to Case Western Reserve University (Cleveland).

"Methods and compositions for detecting esophageal neoplasias and/or metaplasias in the esophagus" was invented by Sanford D. Markowitz (Pepper Pike, Ohio), Helen Moinova (Beachwood, Ohio), Amitabh Chak (University Heights, Ohio), Joseph Willis (Shaker Heights, Ohio) and Thomas LaFramboise (Shaker Heights, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides methods for identifying genomic loci (e.g., vimentin and/or SqBE18) that are differentially methylated in metaplasias (e.g., Barrett's esophagus) and/or neoplastic cancers (e.g., esophagea...