US Patent Issued to CASE WESTERN RESERVE UNIVERSITY on Feb. 17 for "Compositions and methods of modulating S-nitrosylation" (Ohio Inventor)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,551,467, issued on Feb. 17, was assigned to CASE WESTERN RESERVE UNIVERSITY (Cleveland).

"Compositions and methods of modulating S-nitrosylation" was invented by Jonathan S. Stamler (Shaker Heights, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of treating cardiovascular disorders and diseases in a subject in need thereof includes administering to the subject an ADH inhibitor, AKR inhibitor, and/or SNO-CoAR inhibitor at an amount(s) effective to promote S-nitrosylation of proteins in the subject, wherein the ADH inhibitor and/or SNO-CoAR inhibitor is not an ADH3 inhibitor."

The patent was filed on Aug. 30, 2022, under Application No. 17/...