ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,508,427, issued on Dec. 30, was assigned to CASE WESTERN RESERVE UNIVERSITY (Cleveland).

"Closed-loop vagus nerve stimulation for the treatment of obesity" was invented by Dominique Durand (Shaker Heights, Ohio), Joseph Marmerstein (Cleveland) and Grant McCallum (South Euclid, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Obesity and other medical conditions can be managed using a closed-loop system, which uses one or more implantable recording electrodes, a processing device, and one or more implantable stimulating electrodes. The one or more implantable recording electrodes can record signals from a portion of one or more subdiaphragmatic branch...