US Patent Issued to CASE WESTERN RESERVE UNIVERSITY on Aug. 5 for "Nanoparticle constructs for systemic co-delivery of anti-tumor agents" (Ohio Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,118, issued on Aug. 5, was assigned to CASE WESTERN RESERVE UNIVERSITY (Cleveland).

"Nanoparticle constructs for systemic co-delivery of anti-tumor agents" was invented by Efstathios Karathanasis (Solon, Ohio), Prabhani Atukorale (Cleveland), Wyatt Becicka (Cleveland) and Peter Bielecki (Cleveland).

According to the abstract* released by the U.S. Patent & Trademark Office: "An immuno-nanoparticle construct for use in therapeutic applications includes a nanocarrier, a stimulator of interferon (IFN) genes (STING) pathway agonist, and a toll-like receptor 4 (TLR4) agonist, wherein the STING pathway agonist and the TLR4 agonist are co-loaded in the nanoparticle carrier."

The patent w...