US Patent Issued to Caribou Biosciences on Oct. 7 for "Humanized BCMA antibody and BCMA-CAR-T cells" (California Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,152, issued on Oct. 7, was assigned to Caribou Biosciences Inc. (Berkeley, Calif.).

"Humanized BCMA antibody and BCMA-CAR-T cells" was invented by Lijun Wu (Berkeley, Calif.) and Vita Golubovskaya (Richmond, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to a humanized BCMA single-chain variable fragment (scFv), comprising VH having the amino acid sequence of SEQ ID NO: 3 and VL having the amino acid sequence of SEQ ID NO: 5. The present invention is also directed to a BCMA chimeric antigen receptor fusion protein comprising from N-terminus to C-terminus: (i) a single-chain variable fragment (scFv) of the pres...