ALEXANDRIA, Va., June 17 -- United States Patent no. 12,311,033, issued on May 27, was assigned to Capstan Therapeutics Inc..
"Lipid nanoparticle formulations and compositions" was invented by Priya Prakash Karmali (San Diego), Steven Tanis (Carlsbad, Calif.) and Yanjie Bao (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compositions of lipid nanoparticles (LNP) comprising an ionizable cationic lipid, a phospholipid, a sterol, and a PEG-lipid (non-functionalized and optionally functionalized). The functionalized PEG-lipid can be conjugated with a binding moiety to create a targeted LNP (tLNP). The disclosed tLNP preferentially deliver a nucleic acid molecule or other negatively charge...