ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,397,036, issued on Aug. 26, was assigned to Cambridge Enterprise Ltd. (Cambridgeshire, Great Britain).
"Peptide exchange protein" was invented by Louise Helen Boyle (Cambridgeshire, Great Britain), Andreas Heinrich Neerincx (Cambridgeshire, Great Britain) and Florin Tudor Ilca (Cambridgeshire, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to peptide-exchange proteins comprising the luminal domain of TAP-binding protein-related (TAPBPR), which functions as a MHC class I peptide-exchange catalyst when presented to mammalian cells either as a soluble extracellular protein or as a membrane bound cell surface protein. Th...