US Patent Issued to California Institute of Technology on Sept. 23 for "Engineered enzymes and method for the synthesis of diverse tyrosine analogs" (California Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,534, issued on Sept. 23, was assigned to California Institute of Technology (Pasadena, Calif.).

"Engineered enzymes and method for the synthesis of diverse tyrosine analogs" was invented by Patrick J. Almhjell (Pasadena, Calif.) and Frances H. Arnold (Pasadena, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is an engineered tryptophan synthase Beta-subunit (TrpB) that catalyzes the synthesis of tyrosine, tyrosine analogs, or salts thereof. Also provided herein are methods for preparing tyrosine, tyrosine analogs, or a salt thereof using the engineered TrpB described herein."

The patent was filed on Nov. 10, 2022, under Appli...