ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,467,917, issued on Nov. 11, was assigned to California Institute of Technology (Pasadena, Calif.).

"Reconstructing human early embryogenesis in vitro with pluripotent stem cells" was invented by Magdalena D. Zernicka-Goetz (Pasadena, Calif.), Berna Sozen (Pasadena, Calif.) and Victoria Jorgensen (Pasadena, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein include methods and compositions for in vitro culture of three-dimensional expanded pluripotency (EP) structures from pluripotent stem cells. In some embodiments, the method can include generating expanded pluripotent stem cells (EPSCs) and culturing the EPSCs in a composition capa...