ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,230, issued on May 13, was assigned to California Institute of Technology (Pasadena, Calif.).

"Synthetic system for tunable thresholding of protein signals" was invented by Lucy S. Chong (Pasadena, Calif.), Ronghui Zhu (Pasadena, Calif.), Xiaofei Ge (Beijing), Michael B. Elowitz (Pasadena, Calif.) and Mark W. Budde (Arcadia, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein include methods, compositions, and kits suitable for use in thresholding of protein signals. There are provided, in some embodiments, synthetic protein circuits that respond to inputs only above or below a certain threshold concentration. In some embodiments,...