US Patent Issued to California Institute of Technology on May 13 for "Method for robust control of gene expression" (California Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,236, issued on May 13, was assigned to California Institute of Technology (Pasadena, Calif.).

"Method for robust control of gene expression" was invented by Michael J. Flynn (Pasadena, Calif.), Michael B. Elowitz (Pasadena, Calif.), Acacia Hori (Pasadena, Calif.) and Viviana Gradinaru (La Canada Flintridge, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein include methods, compositions, and kits suitable for robust and tunable control of payload gene expression. Some embodiments provide rationally designed circuits, including miRNA-level and/or protein-level incoherent feed-forward loop circuits, that maintain the expression of ...