US Patent Issued to California Institute of Technology on March 25 for "Pairing antigen specificity of a T cell with T cell receptor sequences" (California Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,613, issued on March 25, was assigned to California Institute of Technology (Pasadena, Calif.).

"Pairing antigen specificity of a T cell with T cell receptor sequences" was invented by James R. Heath (Pasadena, Calif.), Songming Peng (San Mateo, Calif.) and Alphonsus Hon-Chung Ng (Pasadena, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for identifying antigen-specific T cells, including determining paired T cell receptor sequences for a specific antigen, are described. Compositions and methods for identifying neoantigen-specific T cells are also described. Microfluidic devices useful for identifying antigen-specific...