ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,504, issued on Feb. 18, was assigned to C4 Therepeutics Inc. (Watertown, Mass.).
"Spirocyclic compounds" was invented by Christopher G. Nasveschuk (Stoneham, Mass.), Fabian Dey (Basel, Switzerland), Annick Goergler (Basel, Switzerland), Bernd Kuhn (Reinach BL, Switzerland), Roger Norcross (Basel, Switzerland), Stephan Roever (Basel, Switzerland) and Philipp Schmid (Basel, Switzerland).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compounds which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and their use for the treatment of abnormal cellular proliferation. The present invention also provides com...