US Patent Issued to C4 THERAPEUTICS on Sept. 23 for "Bicyclic-substituted glutarimide cereblon binders" (British, American Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,220, issued on Sept. 23, was assigned to C4 THERAPEUTICS INC. (Watertown, Mass.).

"Bicyclic-substituted glutarimide cereblon binders" was invented by Christopher G. Nasveschuk (Stoneham, Mass.), Kiel Lazarski (Boston), Yanke Liang (Belmont, Mass.), Alexander W. Hird (Belmont, Mass.), Ning Yin (Lexington, Mass.), Andrew Charles Good (Bideford, Great Britain), Hongwei Huang (Bedford, Mass.), Scott Joseph Eron (Waltham, Mass.) and Gesine Kerstin Veits (Somerville, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention provides Degron compounds which bind to cereblon which is a component of the E3 ubiquitin ligase. The Degrons provided her...