ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,740, issued on Oct. 14, was assigned to C4 THERAPEUTICS INC. (Watertown, Mass.).
"N/O-linked degrons and degronimers for protein degradation" was invented by Andrew J. Phillips (Littleton, Colo.), Christopher G. Nasveschuk (Stoneham, Mass.), James A. Henderson (Weston, Mass.), Yanke Liang (Belmont, Mass.), Minsheng He (Andover, Mass.), Martin Duplessis (Somerville, Mass.) and Chi-Li Chen (Newton, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention provides Degronimers that have E3 Ubiquitin Ligase targeting moieties (Degrons) that can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and me...