US Patent Issued to Brown University on March 4 for "Multi-compartment device containing human three-dimensional (3D) microtissues for toxicity testing" (Rhode Island, Massachusetts Inventors)

ALEXANDRIA, Va., March 5 -- United States Patent no. 12,241,049, issued on March 4, was assigned to Brown University (Providence, R.I.).

"Multi-compartment device containing human three-dimensional (3D) microtissues for toxicity testing" was invented by Kim Boekelheide (East Greenwich, R.I.), Jeffrey Morgan (Sharon, Mass.), Susan Hall (Saunderstown, R.I.), Hui Li (Cranston, R.I.) and Blanche Ip (Providence, R.I.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This dual-compartment liver co-culture system exposes target microtissue to metabolites, allowing for evaluating toxicity using a standard multi-well plate for high throughput analysis. Discovery scientists can rapidly select lead compounds with desirabl...