ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,559, issued on Dec. 30, was assigned to Brown University (Providence, R.I.).

"Bacterial beta-lactamase responsive hydrogels" was invented by Anita Shukla (East Greenwich, R.I.), Dahlia Alkekhia (Providence, R.I.) and Akram Abbasi (Providence, R.I.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a "host-guest" supramolecular hydrogel. The hydrogel contains an AAm/NVP interpenetrating polymer network (IPN) with supramolecular cross-linkers assembled from Beta-lactam/adamantane-containing guest molecule with host polymeric cyclodextrin (PCD). An advantage of this hydrogel is that because of the molecular association of polymeric c...