US Patent Issued to Brown University, Rhode Island Hospital on Jan. 20 for "Human in vitro cardiotoxicity model" (Rhode Island, Connecticut, Massachusetts Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,694, issued on Jan. 20, was assigned to Brown University (Providence, R.I.) and Rhode Island Hospital (Providence, R.I.).

"Human in vitro cardiotoxicity model" was invented by Kareen L. K. Coulombe (Pawtucket, R.I.), Cassady E. Rupert (New Haven, Conn.), Celinda M. Kofron (Hope, R.I.), Bum-Rak Choi (Warwick, R.I.), Taeyun Kim (Coventry, R.I.) and Ulrike Mende (Norfolk, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The Cardio-Tox Tissue Engineered Model (TEEM) invention provides a robust in vitro model for cardiotoxicity evaluation using three-dimensional (3D) human heart microtissues to quantify dose-dependent changes in electromechanical act...