ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,173, issued on Nov. 4, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).
"Control of cell growth through a temperature feedback loop" was invented by Kathryn L. Aron (Acton, Mass.) and Jeffrey Swanberg (Maynard, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the use of online biomass capacitance monitoring in cultures as a way to control the growth of cells through the use of a temperature control loop. In certain embodiments, a biomass capacitance probe is used to measure the cell density, and a predetermined growth curve is used to adjust the temperature in the culture."
The patent was filed on Nov....