US Patent Issued to Bristol-Myers Squibb on Nov. 25 for "Antibodies modified for transglutaminase conjugation, conjugates thereof, and methods and uses" (California, Washington Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,686, issued on Nov. 25, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).

"Antibodies modified for transglutaminase conjugation, conjugates thereof, and methods and uses" was invented by Pavel Strop (San Mateo, Calif.), Chetana Rao-Naik (Walnut Creek, Calif.), Xiaodi Deng (San Mateo, Calif.), Paul O. Sheppard (Granite Falls, Wash.), Sean Matthew WEST (Union City, Calif.), Jason Michael Hogan (Palo Alto, Calif.) and Sayumi Yamazoe (Mountain View, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Antibodies are modified by replacing amino acids in the heavy chain CH1, CH2, or CH3 or light chain constant region with selected replacement g...