ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,913, issued on Aug. 12, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).
"Methods for detecting anti-drug antibodies" was invented by Weifeng Xu (West Windsor, N.J.) and Renuka C. Pillutla (Bridgewater, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "In certain embodiments, the present invention provides a method for detecting an anti-drug antibody (ADA) in a sample, comprising: a) pre-treating the sample at a high temperature to dissociate the ADA: drug immune complex in the sample; b) isolating the ADA from the sample by a matrix; c) retrieving the ADA from the matrix using a buffer; and d) detecting the ADA in a cell-based assay or...