US Patent Issued to Braskem on Aug. 5 for "Co-production pathway for 3-HPA and acetyl-CoA derivatives from malonate semialdehyde" (Brazilian Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,580, issued on Aug. 5, was assigned to Braskem S.A. (Sao Paulo).

"Co-production pathway for 3-HPA and acetyl-CoA derivatives from malonate semialdehyde" was invented by Beatriz Leite Magalhaes (Campinas, Brazil), Paulo Moises Raduan Alexandrino (Campinas, Brazil) and Felipe Galzerani (Paulinia, Brazil).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods for utilizing genetically modified microbes to co-produce 3-hydroxypropionic acid (3-HP) and acetyl-CoA, and derivatives thereof from malonate semialdehyde as a common single intermediate. The disclosure further provides modified microbe that co-produce the 3-HP and a...