US Patent Issued to Brandeis University on March 18 for "Compositions and methods for modulating kinase activity" (Massachusetts Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,253,514, issued on March 18, was assigned to Brandeis University (Waltham, Mass.).

"Compositions and methods for modulating kinase activity" was invented by Dorothee Kern (Waltham, Mass.) and Adelajda Zorba (Waltham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features an antibody mimetic, or an antigen binding fragment thereof, that specifically binds to an allosteric site of Aurora A kinase, therapeutic compositions comprising this antibody mimetic, and the use of the monobody to modulate Aurora A kinase for the treatment of cancer."

The patent was filed on July 20, 2021, under Application No. 17/380,704.

*For further...