ALEXANDRIA, Va., June 10 -- United States Patent no. 12,290,576, issued on May 6, was assigned to BRACCO IMAGING S.P.A. (Milan).
"Manufacturing of dimeric contrast agents" was invented by Andrea Banin (Collegno, Italy), Andrea Barale (Bibiana, Italy), Valeria Boi (Strambino, Italy), Sonia Gazzetto (Cascinette d'Ivrea, Italy) and Federica Buonsanti (Turin, Italy).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a process for the preparation of dimeric contrast agents for use in Magnetic resonance Imaging (MRI), in particular [Mu-[1-[bis[2-(hydroxy-KappaO)-3-[4,7,10-tris[(carboxy-KappaO)methyl]-1,4,7,10-tetraazacyclododec-1-yl-KappaN1,KappaN4,KappaN7,KappaN10]propyl]amino]-1-deoxy-D-gluci...