ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,180, issued on May 13, was assigned to BRACCO IMAGING S.P.A. (Milan).
"Manufacturing of protected DO3A" was invented by Aurelia Ferrigato (Trecate, Italy) and Sonia Gazzetto (Cascinette d'Ivrea, Italy).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a process for the one-step preparation and isolation of a protected DO3A such as DO3A-tri-tert-butyl ester as a solid salt."
The patent was filed on Dec. 9, 2020, under Application No. 17/784,232.
*For further information, including images, charts and tables, please visit: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html...