ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,384, issued on June 3, was assigned to BOW RIVER LLC (Corona del Mar, Calif.).

"Methods of treatment" was invented by Sundar Srinivasan (Corona Del Mar, Calif.) and Christina Chow Wallen (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides for methods of treating a patient with a CYP3A4 substrate drug, wherein the patient is treated with posaconazole. In some embodiments, the patient stops posaconazole treatment, waits for at least 2 days, and then is treated with the CYP3A4 substrate drug as soon as it is safe to do so. In some embodiments, treatment with the CYP3A4 substrate drug is delayed for about 2-42 days aft...