ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,218, issued on Sept. 23, was assigned to Boehringer Ingelheim International GmbH (Ingelheim am Rhein, Germany).

"Substituted pyrazine-carboxamide derivatives" was invented by Roland Pfau (Mittelbiberach, Germany), Georg Dahmann (Biberach, Germany), Johann Faustus Du Hoffmann (Biberach an der Riss, Germany), Kai Gerlach (Mittelbiberach, Germany), Riccardo Giovaninni (Biberach an der Riss, Germany), Christoph Hohn (Freiburg, Germany), Stefan Just (Biberach an der Riss, Germany), Thorsten Lehmann (Biberach, Germany), Anton Pekcec (Biberach, Germany), Stefan Peters (Biberach an der Riss, Germany), Julia Schlichtiger (Biberach, Germany), Heiko Sommer (Warthausen, Germany), Christian S...