ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,456, issued on Oct. 21, was assigned to Boehringer Ingelheim International GmbH (Ingelheim am Rhein, Germany).
"Method for producing spesolimab" was invented by Thomas Wucherpfennig (Ingelheim am Rhein, Germany) and Rico Lippmann (Ingelheim am Rhein, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for producing the anti-IL36R antibody spesolimab. More specifically, the present invention relates to a method of producing spesolimab with a serum-free cell culture medium in a fed-batch culture in the presence of reduced copper and increased iron concentrations. In addition, the present invention relates t...