US Patent Issued to Boehringer Ingelheim International on April 22 for "Isoindolinone substituted indoles and derivatives as RAS inhibitors" (Austrian, French Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,099, issued on April 22, was assigned to Boehringer Ingelheim International GmbH (Ingelheim am Rhein, Germany).

"Isoindolinone substituted indoles and derivatives as RAS inhibitors" was invented by Andreas Mantoulidis (Vienna), Andreas Gollner (Vienna), Dirk Kessler (Vienna), Laetitia Janine Martin (Saint Louis, France) and Harald Weinstabl (Vienna).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to new isoindolinone or isobenzofuranone substituted indoles and derivatives of formula (I) wherein the groups R1 to R7, R10 and n have the meanings given in the claims and specification, their use as inhibitors of RAS-family prot...