US Patent Issued to Board of Regents, The University of Texas System on Sept. 2 for "Poly(A)-ClickSeq click-chemistry for next generation 3-end sequencing without RNA enrichment or fragmentation" (Texas Inventors)

ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,404,296, issued on Sept. 2, was assigned to Board of Regents, The University of Texas System (Austin, Texas).

"Poly(A)-ClickSeq click-chemistry for next generation 3-end sequencing without RNA enrichment or fragmentation" was invented by Andrew Routh (Galveston, Texas), Eric J. Wagner (Galveston, Texas), Ping Ji (Houston) and Elizabeth Jaworski (La Marque, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes a method and kit for cDNA synthesis of a 3'UTR/poly(A) tail junction of cellular RNA comprising: obtaining RNA comprising a 3'UTR/poly(A) junction and a poly(a) tail; combining the RNA with three terminating nucleotide...