ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,582, issued on Oct. 14, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).
"Biothiol-activatable probe and method of use" was invented by Jie Zheng (Plano, Texas) and Xingya Jiang (Richardson, Texas).
According to the abstract* released by the U.S. Patent & Trademark Office: "A biothiol-activatable composition is disclosed that is configured to dissociate in the presence of a concentration of biomolecules that are excreted normally by a liver of a living subject comprising a noble metal nanoparticle, a reporter molecule, a linker molecule that is conjugated to the noble metal nanoparticle and to the reporter molecule, but displaceable in the presenc...