US Patent Issued to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM on May 27 for "Methods for enhancing immune checkpoint blockade therapy by modulating the microbiome" (Texas Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,996, issued on May 27, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).

"Methods for enhancing immune checkpoint blockade therapy by modulating the microbiome" was invented by Jennifer Wargo (Houston) and Vancheswaran Gopalakrishnan (Houston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods and compositions for the treatment of cancer by modulating the microbiome to enhance the efficacy of immune checkpoint blockade. The microbiome may be modulated by the administration of butyrate and/or butyrate-producing bacteria. Also provided herein are methods of determining a response to an immune chec...