ALEXANDRIA, Va., June 19 -- United States Patent no. 12,329,744, issued on June 17, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).
"Methods of preparing extrudates" was invented by Feng Zhang (Pflugerville, Texas), Abbe Miller (Austin, Texas), Siyuan Huang (Austin, Texas) and Robert O. Williams III (Austin, Texas).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods of preparing amorphous drug formulations through hot melt extrusion which result in decreased decomposition of the desired drug are provided herein. Also provided are methods and compositions which further comprise a pharmaceutically acceptable thermoplastic polymer. In some embodiments, these ...