ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,266, issued on July 15, was assigned to Board of Regents, The University of Texas System (Austin, Texas).
"Tiled ClickSeq for targeted virus whole genome sequencing" was invented by Andrew Routh (Galveston, Texas) and Elizabeth Jaworski (La Marque, Texas).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes a method and kit for single-primer tiled sequencing comprising: reverse transcribing a target nucleic acid with multiple tiled primers spaced along the genome, each only targeting one annealing site to form amplicons in the presence of terminating 3' azido nucleotides to incorporate the terminating 3' azido nucleotides int...