ALEXANDRIA, Va., June 17 -- United States Patent no. 12,311,060, issued on May 27, was assigned to Biscayne Neurotherapeutics Inc. (Rockville, Md.).

"Modified release pharmaceutical compositions of huperzine and methods of using the same" was invented by Stephen D. Collins (Lake Forest, Ill.), Peter Goldstein (Hollywood, Fla.) and Joshua T. Johnstone (Apex, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application discloses pharmaceutical compositions for modified release of huperzine. The pharmaceutical compositions and methods described herein, allow for dosing of huperzine at higher therapeutic thresholds, while avoiding rapid serum peak plasma levels, thereby avoiding the adverse nausea...