ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,200, issued on Dec. 9, was assigned to Birstol Myers-Squibb Co. (Princeton, N.J.).

"NLRP3 modulators" was invented by Scott Hunter Watterson (Pennington, N.J.), Hua Gong (King of Prussia, Pa.), Kristin Williams (Belle Mead, N.J.), Ashvinikumar V. Gavai (Princeton Junction, N.J.), Prasanna Sivaprakasam (Plainsboro, N.J.) and Yong Zhang (West Windsor, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compounds of Formula (I), wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subje...