ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,970, issued on April 15, was assigned to BIOVERATIV THERAPEUTICS INC. (Waltham, Mass.).
"Optimized factor IX gene" was invented by Siyuan Tan (Lexington, Mass.), Robert T. Peters (Needham, Mass.) and Tongyao Liu (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides codon optimized Factor IX sequences, vectors and host cells comprising codon optimized Factor IX sequences, polypeptides encoded by codon optimized Factor IX sequences, and methods of producing such polypeptides. The present invention also provides methods of treating bleeding disorders such as hemophilia comprising administering to the subject a c...