US Patent Issued to BIOVERATIV THERAPEUTICS, PUGET SOUND BLOOD CENTER on July 29 for "Methods of reducing immunogenicity against factor VIII in individuals undergoing factor VIII therapy" (Massachusetts, Washington Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,747, issued on July 29, was assigned to BIOVERATIV THERAPEUTICS INC. (Waltham, Mass.) and PUGET SOUND BLOOD CENTER (Seattle).

"Methods of reducing immunogenicity against factor VIII in individuals undergoing factor VIII therapy" was invented by Haiyan Jiang (Belmont, Mass.), Tongyao Liu (Lexington, Mass.), Sriram Krishnamoorthy (Medford, Mass.), Neil Josephson (Seattle) and Glenn Pierce (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of administering chimeric and hybrid Factor VIII (FVIII) polypeptides comprising FVIII and Fc to subjects at risk of developing inhibitory FVIII immune responses,...